Genome sequence analysis suggests coevolution of the DIS, SD, and Psi hairpins in HIV-1 genomes

HIV-1 RNA dimerization is a critical step in viral life cycle. It is a prerequisite for genome packaging and plays an important role in reverse transcription and recombination. Dimerization is promoted by the DIS (dimerization initiation site) hairpin located in the 5′ leader of HIV-1 genome. Despit...

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Bibliographic Details
Main Authors: Margarita.I. Zarudnaya, Andriy.L. Potyahaylo, Iryna.M. Kolomiets, Leonid.G. Gorb
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Virus Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0168170222002386