The serotonin receptor 5-HT2A modulates lifespan and protein feeding in Drosophila melanogaster

The conserved neurotransmitter serotonin has been shown to be an important modulator of lifespan in specific nutritional contexts; however, it remained unclear how serotonin signaling influences lifespan under normal conditions. Here, we show that serotonin signaling through the 5-HT2A receptor infl...

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Bibliographic Details
Main Authors: Allyson S. Munneke, Tuhin S. Chakraborty, Saige S. Porter, Christi M. Gendron, Scott D. Pletcher
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Aging
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fragi.2022.1068455/full