Canine polarized macrophages express distinct functional and transcriptomic profiles

Canine polarized macrophages express distinct functional and transcriptomic profiles

Macrophage differentiation and function in disease states is highly regulated by the local microenvironment. For example, macrophage exposure to IFN-γ (interferon gamma) initiates the development of inflammatory (M1) macrophages, which acquire anti-tumoral and antimicrobial activity, while exposure...

Full description

Bibliographic Details
Main Authors: Lyndah Chow, Sirikul Soontararak, William Wheat, Dylan Ammons, Steven Dow
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Veterinary Science
Subjects:
RNA sequencing
transcriptome
dog
cytokines
macrophage
macrophage phenotype and function
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2022.988981/full

Internet

https://www.frontiersin.org/articles/10.3389/fvets.2022.988981/full

Similar Items