Developing Biliary Atresia-like Model by Treating Human Liver Organoids with Polyinosinic:Polycytidylic Acid (Poly (I:C))

Developing Biliary Atresia-like Model by Treating Human Liver Organoids with Polyinosinic:Polycytidylic Acid (Poly (I:C))

Background: We explored the feasibility of creating BA-like organoids by treating human liver organoids with Polyinosinic:Polycytidylic acid (Poly I:C). Methods: Organoids were developed from the liver parenchyma collected during Kasai portoenterostomy (BA) and surgery for other liver disorders (non...

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Bibliographic Details
Main Authors: Patrick Ho-Yu Chung, Rosana Ottakandathil Babu, Zhongluan Wu, Kenneth Kak-Yuen Wong, Paul Kwong-Hang Tam, Vincent Chi-Hang Lui
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Current Issues in Molecular Biology
Subjects:
biliary atresia
liver
inflammation
organoids
transcriptomic
Polyinosinic:Polycytidylic acid
Online Access:https://www.mdpi.com/1467-3045/44/2/45

Internet

https://www.mdpi.com/1467-3045/44/2/45

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