RETSAT Mutation Selected for Hypoxia Adaptation Inhibits Tumor Growth

RETSAT Mutation Selected for Hypoxia Adaptation Inhibits Tumor Growth

Hypoxia occurs not only in natural environments including high altitude, underground burrows and deep sea, but also in human pathological conditions, such as hypoxic solid tumors. It has been well documented that hypoxia related signaling pathway is associated with a poor clinical outcome. Our group...

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Bibliographic Details
Main Authors: Xiulin Jiang, Yaomei He, Qiushuo Shen, Lincan Duan, Yixiao Yuan, Lin Tang, Yulin Shi, Baiyang Liu, Haoqing Zhai, Peng Shi, Cuiping Yang, Yongbin Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
retinol saturase (RETSAT)
hypoxia adaptation
evolution
Pin1
skin cutaneous melanoma (SKCM)
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.744992/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.744992/full

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