A Novel Radiotherapeutic Approach to Treat Bulky Metastases Even From Cutaneous Squamous Cell Carcinoma: Its Rationale and a Look at the Reliability of the Linear-Quadratic Model to Explain Its Radiobiological Effects

A Novel Radiotherapeutic Approach to Treat Bulky Metastases Even From Cutaneous Squamous Cell Carcinoma: Its Rationale and a Look at the Reliability of the Linear-Quadratic Model to Explain Its Radiobiological Effects

IntroductionMetastatic cutaneous squamous cell carcinoma (cSCC) is a very rare condition. The lack of definition of an oligometastatic subgroup means that there is no consensus for its treatment, unlike the mucosal head and neck counterpart. Like the latter, the cutaneous form is able to develop bul...

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Bibliographic Details
Main Authors: Gianluca Ferini, Paolo Castorina, Vito Valenti, Salvatore Ivan Illari, Ilias Sachpazidis, Luigi Castorina, Maurizio Marrale, Stefano Pergolizzi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Oncology
Subjects:
lattice radiotherapy
tumor control probability (TCP)
normal tissue complication probability (NTCP)
spatially fractionated radiation therapy
immunotherapy
metabolic tumor volume
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.809279/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.809279/full

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