Characterization, Recombinant Production and Structure-Function Analysis of NvCI, A Picomolar Metallocarboxypeptidase Inhibitor from the Marine Snail <i>Nerita versicolor</i>

Characterization, Recombinant Production and Structure-Function Analysis of NvCI, A Picomolar Metallocarboxypeptidase Inhibitor from the Marine Snail <i>Nerita versicolor</i>

A very powerful proteinaceous inhibitor of metallocarboxypeptidases has been isolated from the marine snail <i>Nerita versicolor</i> and characterized in depth. The most abundant of four, very similar isoforms, NvCla, was taken as reference and N-terminally sequenced to obtain a 372-nucl...

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Bibliographic Details
Main Authors: Giovanni Covaleda-Cortés, Martha Hernández, Sebastián Alejandro Trejo, Manuel Mansur, Sergi Rodríguez-Calado, Javier García-Pardo, Julia Lorenzo, Josep Vendrell, María Ángeles Chávez, Maday Alonso-del-Rivero, Francesc Xavier Avilés
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Marine Drugs
Subjects:
<i>Nerita versicolor</i>
proteinaceous inhibitor
recombinant production
carboxypeptidase
picomolar inhibition
biotechnological and biomedical applications
Online Access:https://www.mdpi.com/1660-3397/17/9/511

Internet

https://www.mdpi.com/1660-3397/17/9/511

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