Boolean logic in synthetic biology and biomaterials: Towards living materials in mammalian cell therapeutics

Boolean logic in synthetic biology and biomaterials: Towards living materials in mammalian cell therapeutics

Abstract Background: The intersection of synthetic biology and biomaterials promises to enhance safety and efficacy in novel therapeutics. Both fields increasingly employ Boolean logic, which allows for specific therapeutic outputs (e.g., drug release, peptide synthesis) in response to inputs such a...

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Bibliographic Details
Main Authors: Eric M. Bressler, Sarah Adams, Rong Liu, Yolonda L. Colson, Wilson W. Wong, Mark W. Grinstaff
Format: Article
Language:English
Published: Wiley 2023-07-01
Series:Clinical and Translational Medicine
Subjects:
biomaterials
boolean logic
CAR T cells
cell therapy
drug delivery
synthetic biology
Online Access:https://doi.org/10.1002/ctm2.1244

Internet

https://doi.org/10.1002/ctm2.1244

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