Identification of <named-content content-type="genus-species">Clostridioides difficile</named-content>-Inhibiting Gut Commensals Using Culturomics, Phenotyping, and Combinatorial Community Assembly

ABSTRACT A major function of the gut microbiota is to provide colonization resistance, wherein pathogens are inhibited or suppressed below infectious levels. However, the fraction of gut microbiota required for colonization resistance remains unclear. We used culturomics to isolate a gut microbiota...

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Bibliographic Details
Main Authors: Sudeep Ghimire, Chayan Roy, Supapit Wongkuna, Linto Antony, Abhijit Maji, Mitchel Chan Keena, Andrew Foley, Joy Scaria
Format: Article
Language:English
Published: American Society for Microbiology 2020-02-01
Series:mSystems
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mSystems.00620-19