Large scale sequence alignment via efficient inference in generative models
Abstract Finding alignments between millions of reads and genome sequences is crucial in computational biology. Since the standard alignment algorithm has a large computational cost, heuristics have been developed to speed up this task. Though orders of magnitude faster, these methods lack theoretic...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-05-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-34257-x |