Human Dendritic Cells Transmit Enterovirus A71 via Heparan Sulfates to Target Cells Independent of Viral Replication

Human Dendritic Cells Transmit Enterovirus A71 via Heparan Sulfates to Target Cells Independent of Viral Replication

ABSTRACT Enterovirus A71 (EV-A71) is a causative agent of life-threatening neurological diseases in young children. EV-A71 is highly infectious but it remains unclear how the virus disseminates from primary entry sites—the mucosa of the respiratory tract or the intestine—to secondary replication sit...

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Bibliographic Details
Main Authors: Leanne C. Helgers, Michel S. Bhoekhan, Dasja Pajkrt, Katja C. Wolthers, Teunis B. H. Geijtenbeek, Adithya Sridhar
Format: Article
Language:English
Published: American Society for Microbiology 2022-12-01
Series:Microbiology Spectrum
Subjects:
dendritic cells
enterovirus
picornavirus
receptors
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02822-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.02822-22

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