Changes in DNA methylation in naïve T helper cells regulate the pathophysiological state in minimal-change nephrotic syndrome

Changes in DNA methylation in naïve T helper cells regulate the pathophysiological state in minimal-change nephrotic syndrome

Abstract Background DNA methylation plays a crucial role in regulating transcription, and changes in DNA methylation affect gene expression and disease development. Minimal change nephrotic syndrome (MCNS) has been reported to involve immunological disturbances. Since the characteristic features of...

Full description

Bibliographic Details
Main Authors: Yasuko Kobayashi, Akira Aizawa, Takumi Takizawa, Katsuhide Igarashi, Izuho Hatada, Hirokazu Arakawa
Format: Article
Language:English
Published: BMC 2017-09-01
Series:BMC Research Notes
Subjects:
Nephrotic syndrome
Minimal-change
Children
DNA methylation
Microarray-based integrated analysis of methylation by isoschizomers method
Helper T cell
Online Access:http://link.springer.com/article/10.1186/s13104-017-2719-1

Internet

http://link.springer.com/article/10.1186/s13104-017-2719-1

Similar Items