Bisphenol A exposure triggers endoplasmic reticulum stress pathway leading to ocular axial elongation in mice

Bisphenol A exposure triggers endoplasmic reticulum stress pathway leading to ocular axial elongation in mice

BackgroundOcular axial elongation is one of the features of myopia progression. Endoplasmic reticulum (ER) stress-associated scleral remodeling plays an important role in ocular axial elongation. Bisphenol A (BPA) is one of the most common environmental pollutants and is known to affect various huma...

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Bibliographic Details
Main Authors: Junhan Chen, Shin-ichi Ikeda, Longdan Kang, Kazuno Negishi, Kazuo Tsubota, Toshihide Kurihara
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Medicine
Subjects:
bisphenol A
endoplasmic reticulum stress
ATF6
PERK
sclera
myopia
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2023.1255121/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2023.1255121/full

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