The T cell response to lipid antigens of Mycobacterium tuberculosis

T cells recognize lipid antigens presented by dedicated antigen presenting molecules that belong to the CD1 family. This review discusses the structural properties of CD1 molecules, the nature of mycobacterial lipid antigens, and the phenotypic and functional properties of T cells recognizing mycoba...

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Bibliographic Details
Main Authors: Gennaro eDe Libero, Lucia eMori
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00219/full