Next‐generation sequencing of tissue and circulating tumor DNA: Resistance mechanisms to EGFR targeted therapy in a cohort of patients with advanced non‐small cell lung cancer

Abstract Background Epidermal growth factor receptor‐tyrosine kinase inhibitor (EGFR‐TKI) has been considered as an effective treatment in epidermal growth factor receptor‐mutant (EGFR‐mutant) advanced non‐small cell lung cancer (NSCLC). However, most patients develop acquired resistance eventually....

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Bibliographic Details
Main Authors: Yujun Zhang, Liwen Xiong, Fangfang Xie, Xiaoxuan Zheng, Ying Li, Lei Zhu, Jiayuan Sun
Format: Article
Language:English
Published: Wiley 2021-07-01
Series:Cancer Medicine
Subjects:
Online Access:https://doi.org/10.1002/cam4.3948