Ebola virus VP30 and nucleoprotein interactions modulate viral RNA synthesis
Ebola virus (EBOV) VP30 is a multifunctional protein that plays a role in transcription, but molecular details remain unknown. Here, using X-ray crystallography and minigenome assays, Xuet al. define the interaction between VP30 and a portion of NP that is critical for optimal EBOV RNA synthesis.
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2017-06-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms15576 |