Prioritizing Cancer Genes Based on an Improved Random Walk Method

Identifying driver genes that contribute to cancer progression from numerous passenger genes, although a central goal, is a major challenge. The protein–protein interaction network provides convenient and reasonable assistance for driver gene discovery. Random walk–based methods have been widely use...

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Bibliographic Details
Main Authors: Pi-Jing Wei, Fang-Xiang Wu, Junfeng Xia, Yansen Su, Jing Wang, Chun-Hou Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00377/full