Multiple gene substitution by Target-AID base-editing technology in tomato
Abstract The use of Target activation-induced cytidine deaminase (Target-AID) base-editing technology with the CRISPR-Cas 9 system fused with activation-induced cytidine deaminase (AID) resulted in the substitution of a cytidine with a thymine. In previous experiments focusing on a single target gen...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2020-11-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-020-77379-2 |