Multiple gene substitution by Target-AID base-editing technology in tomato

Abstract The use of Target activation-induced cytidine deaminase (Target-AID) base-editing technology with the CRISPR-Cas 9 system fused with activation-induced cytidine deaminase (AID) resulted in the substitution of a cytidine with a thymine. In previous experiments focusing on a single target gen...

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Bibliographic Details
Main Authors: Johan Hunziker, Keiji Nishida, Akihiko Kondo, Sanae Kishimoto, Tohru Ariizumi, Hiroshi Ezura
Format: Article
Language:English
Published: Nature Portfolio 2020-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-77379-2