Over-expression of BAG-1 in head and neck squamous cell carcinomas (HNSCC) is associated with cisplatin-resistance

Over-expression of BAG-1 in head and neck squamous cell carcinomas (HNSCC) is associated with cisplatin-resistance

Abstract Background In order to improve therapy for head and neck squamous cell carcinoma (HNSCC), biomarkers associated with local and/or distant tumor relapses and cancer drug resistance are urgently needed. This study identified a potential biomarker, Bcl-2 associated athanogene-1 (BAG-1), that i...

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Bibliographic Details
Main Authors: Shutong Liu, Bo Ren, Hang Gao, Suchan Liao, Ying-Xian Zhai, Shirong Li, Xue-Jin Su, Ping Jin, David Stroncek, Zhixiang Xu, Qinghua Zeng, Yulin Li
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Journal of Translational Medicine
Subjects:
Head and neck squamous cell carcinomas
Cisplatin
Drug resistance
Biomarker
BAG-1
BCL-xL
Online Access:http://link.springer.com/article/10.1186/s12967-017-1289-2

Internet

http://link.springer.com/article/10.1186/s12967-017-1289-2

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