A three-stemmed mRNA pseudoknot in the SARS coronavirus frameshift signal.

A wide range of RNA viruses use programmed -1 ribosomal frameshifting for the production of viral fusion proteins. Inspection of the overlap regions between ORF1a and ORF1b of the SARS-CoV genome revealed that, similar to all coronaviruses, a programmed -1 ribosomal frameshift could be used by the v...

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Bibliographic Details
Main Authors: Ewan P Plant, Gabriela C Pérez-Alvarado, Jonathan L Jacobs, Bani Mukhopadhyay, Mirko Hennig, Jonathan D Dinman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-06-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC1110908?pdf=render