SLY1 and Syntaxin 18 specify a distinct pathway for procollagen VII export from the endoplasmic reticulum

SLY1 and Syntaxin 18 specify a distinct pathway for procollagen VII export from the endoplasmic reticulum

TANGO1 binds and exports Procollagen VII from the endoplasmic reticulum (ER). In this study, we report a connection between the cytoplasmic domain of TANGO1 and SLY1, a protein that is required for membrane fusion. Knockdown of SLY1 by siRNA arrested Procollagen VII in the ER without affecting the r...

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Bibliographic Details
Main Authors: Cristina Nogueira, Patrik Erlmann, Julien Villeneuve, António JM Santos, Emma Martínez-Alonso, José Ángel Martínez-Menárguez, Vivek Malhotra
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-05-01
Series:eLife
Subjects:
Collagen
TANGO1
SLY1
Syntaxin 18
export
ER
Online Access:https://elifesciences.org/articles/02784

Internet

https://elifesciences.org/articles/02784

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