SLY1 and Syntaxin 18 specify a distinct pathway for procollagen VII export from the endoplasmic reticulum
TANGO1 binds and exports Procollagen VII from the endoplasmic reticulum (ER). In this study, we report a connection between the cytoplasmic domain of TANGO1 and SLY1, a protein that is required for membrane fusion. Knockdown of SLY1 by siRNA arrested Procollagen VII in the ER without affecting the r...
Main Authors: | Cristina Nogueira, Patrik Erlmann, Julien Villeneuve, António JM Santos, Emma Martínez-Alonso, José Ángel Martínez-Menárguez, Vivek Malhotra |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2014-05-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/02784 |
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