Upregulation of CD109 Promotes the Epithelial-to-Mesenchymal Transition and Stemness Properties of Lung Adenocarcinomas via Activation of the Hippo-YAP Signaling

Upregulation of CD109 Promotes the Epithelial-to-Mesenchymal Transition and Stemness Properties of Lung Adenocarcinomas via Activation of the Hippo-YAP Signaling

Metastasis is the leading cause of death in lung adenocarcinomas. Identifying potential prognostic biomarkers and exploiting regulatory mechanisms could improve the diagnosis and treatment of lung cancer patients. We previously found that cluster of differentiation 109 (CD109) was upregulated in lun...

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Bibliographic Details
Main Authors: Kang-Yun Lee, Tai-Chih Kuo, Chih-Ming Chou, Wen-Jing Hsu, Wei-Cheng Lee, Jia-Zih Dai, Sheng-Ming Wu, Cheng-Wei Lin
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cells
Subjects:
CD109
EMT
lung adenocarcinoma
stemness
YAP
Online Access:https://www.mdpi.com/2073-4409/10/1/28

Internet

https://www.mdpi.com/2073-4409/10/1/28

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