The Effect of Fucoidan on Cellular Oxidative Stress and the CatD-Bax Signaling Axis in MN9D Cells Damaged by 1-Methyl-4-Phenypyridinium

The Effect of Fucoidan on Cellular Oxidative Stress and the CatD-Bax Signaling Axis in MN9D Cells Damaged by 1-Methyl-4-Phenypyridinium

Background: The purpose of this study was to investigate the impact of fucoidan (FUC) on the oxidative stress response and lysosomal apoptotic pathways in the Parkinson disease (PD) cell model.Methods: The Dopaminergic nerve precursor cell line(MN9D) cells that served as a PD model in this study und...

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Bibliographic Details
Main Authors: Zhigang Liang, Zhuli Liu, Xuwen Sun, Manli Tao, Xiao Xiao, Guoping Yu, Xiaomin Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Aging Neuroscience
Subjects:
fucoidan
MN9D cells
1-methyl-4-phenyl pyridine
oxidative stress
lysosome
apoptosis
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2018.00429/full

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https://www.frontiersin.org/article/10.3389/fnagi.2018.00429/full

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