CRISPR/Cas9 mediated Y-chromosome elimination affects human cells transcriptome

CRISPR/Cas9 mediated Y-chromosome elimination affects human cells transcriptome

Abstract Background Sexual dimorphism represents a key concept in the comprehension of molecular processes guiding several sex-specific physiological and pathological mechanisms. It has been reported that genes involved in many disorders show a sex-dependent expression pattern. Moreover, the loss of...

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Bibliographic Details
Main Authors: Ludovica Celli, Patrizia Gasparini, Ginevra Biino, Laura Zannini, Miriana Cardano
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Cell & Bioscience
Subjects:
Y chromosome
Sex differences
RNA-sequencing
Transcriptome
CRISPR/Cas9
Online Access:https://doi.org/10.1186/s13578-024-01198-5

Internet

https://doi.org/10.1186/s13578-024-01198-5

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