Inflammation-Associated Synaptic Alterations as Shared Threads in Depression and Multiple Sclerosis

Inflammation-Associated Synaptic Alterations as Shared Threads in Depression and Multiple Sclerosis

In the past years, several theories have been advanced to explain the pathogenesis of Major Depressive Disorder (MDD), a neuropsychiatric disease that causes disability in general population. Several theories have been proposed to define the MDD pathophysiology such as the classic “monoamine-theory”...

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Bibliographic Details
Main Authors: Antonio Bruno, Ettore Dolcetti, Francesca Romana Rizzo, Diego Fresegna, Alessandra Musella, Antonietta Gentile, Francesca De Vito, Silvia Caioli, Livia Guadalupi, Silvia Bullitta, Valentina Vanni, Sara Balletta, Krizia Sanna, Fabio Buttari, Mario Stampanoni Bassi, Diego Centonze, Georgia Mandolesi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Cellular Neuroscience
Subjects:
multiple sclerosis
major depressive disorder
excitotoxicity
antidepressant drugs
cytokines
synaptopathy
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.00169/full

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https://www.frontiersin.org/article/10.3389/fncel.2020.00169/full

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