Novel role of AMPK in cocaine reinforcement via regulating CRTC1

Novel role of AMPK in cocaine reinforcement via regulating CRTC1

Abstract Repeated cocaine exposure causes compensatory neuroadaptations in neurons in the nucleus accumbens (NAc), a region that mediates reinforcing effects of drugs. Previous studies suggested a role for adenosine monophosphate-activated protein kinase (AMPK), a cellular energy sensor, in modulati...

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Bibliographic Details
Main Authors: Xiao-Xing Liu, Fang-Lin Liu, Xin Li, Tang-Sheng Lu, Yi-Xiao Luo, Min Jian, Kai Yuan, Shi-Qiu Meng, Yan-Ping Bao, Jie Shi, Lin Lu, Ying Han
Format: Article
Language:English
Published: Nature Publishing Group 2022-12-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-022-02299-w

Internet

https://doi.org/10.1038/s41398-022-02299-w

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