Effective, Long-Term, Neutrophil Depletion Using a Murinized Anti-Ly-6G 1A8 Antibody

Effective, Long-Term, Neutrophil Depletion Using a Murinized Anti-Ly-6G 1A8 Antibody

Neutrophils are crucial innate immune cells but also play key roles in various diseases, such as cancer, where they can perform both pro- and anti-tumorigenic functions. To study the function of neutrophils in vivo, these cells are often depleted using Ly-6G or Gr-1 depleting antibodies or genetic “...

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Bibliographic Details
Main Authors: Patricia A. Olofsen, Marjolein C. Stip, J. H. Marco Jansen, Chilam Chan, Maaike Nederend, Ralph G. Tieland, Maria Tsioumpekou, Jeanette H. W. Leusen
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Cells
Subjects:
neutrophils
neutrophil depletion
in vivo neutrophil targeting
immunotherapy
cancer
Online Access:https://www.mdpi.com/2073-4409/11/21/3406

Internet

https://www.mdpi.com/2073-4409/11/21/3406

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