Estimation of pKa, Analgesic, CNS Depressant Activities of Imidazolinone Derivatives By Correlation With Theoretical Parameters Based on Quantum Chemical Method

Regression analysis is used for the estimation of the pKa values, %analgesic activity (%AA) and % decreasing activity of central nervous system (CNS) depressant property (%DA) of eight substituted imidazolin-5(4H)-ones by using various types of descriptors as parameters. These parameters are based o...

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Bibliographic Details
Main Author: Emad A. S. Al-Hyali
Format: Article
Language:Arabic
Published: College of Education for Pure Sciences 2018-12-01
Series:مجلة التربية والعلم
Subjects:
Online Access:https://edusj.mosuljournals.com/article_159296_8b0b36be909c6320d7ef05892de61e53.pdf