Insight into the molecular recognition mechanism of the coactivator NCoA1 by STAT6

Abstract Crucial for immune and anti-inflammatory cellular responses, signal transducer and activator of transcription 6 (STAT6) regulates transcriptional activation in response to interleukin-4 and -13 -induced tyrosine phosphorylation by direct interaction with coactivators. The interaction of STA...

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Bibliographic Details
Main Authors: Luigi Russo, Karin Giller, Edith Pfitzner, Christian Griesinger, Stefan Becker
Format: Article
Language:English
Published: Nature Portfolio 2017-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-17088-5