PARP Inhibitors in the Treatment of Prostate Cancer: From Scientific Rationale to Clinical Development
Prostate cancer (PC) treatment has reached a milestone with the introduction of poly(ADP-ribose) polymerase (PARP) inhibitors. PARP inhibitors (PARPi) induce breaks in single-stranded and/or double-stranded DNA, resulting in synthetic lethality in cancer cells lacking functional homologous recombi...
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| Format: | Article |
| Language: | English |
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Korean Society for Sexual Medicine and Andrology
2024-04-01
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| Series: | The World Journal of Men's Health |
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