Quantification of host proteomic responses to genotype 4 hepatitis E virus replication facilitated by pregnancy serum

Quantification of host proteomic responses to genotype 4 hepatitis E virus replication facilitated by pregnancy serum

Abstract Background Hepatitis E virus (HEV) infection is a common cause of acute hepatitis worldwide and causes approximately 30% case fatality rate among pregnant women. Pregnancy serum (PS), which contains a high concentration of estradiol, facilitates HEV replication in vitro through the suppress...

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Bibliographic Details
Main Authors: Zhongyao Qian, Chao Cong, Yi Li, Yanhong Bi, Qiuxia He, Tengyuan Li, Yueping Xia, Liangheng Xu, Houfack K. Mickael, Wenhai Yu, Jiankun Liu, Daqiao Wei, Fen Huang
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Virology Journal
Subjects:
Hepatitis E virus
Pregnancy
Proteomic analysis
iTRAQ
Virus-host interactions
Online Access:https://doi.org/10.1186/s12985-023-02080-5

Internet

https://doi.org/10.1186/s12985-023-02080-5

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