Direct observation of the myosin Va recovery stroke that contributes to unidirectional stepping along actin.

Myosins are ATP-driven linear molecular motors that work as cellular force generators, transporters, and force sensors. These functions are driven by large-scale nucleotide-dependent conformational changes, termed "strokes"; the "power stroke" is the force-generating swinging of...

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Bibliographic Details
Main Authors: Katsuyuki Shiroguchi, Harvey F Chin, Diane E Hannemann, Eiro Muneyuki, Enrique M De La Cruz, Kazuhiko Kinosita
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3075224?pdf=render