Long Noncoding RNA GAS5 Promotes Osteogenic Differentiation of Human Periodontal Ligament Stem Cells by Regulating GDF5 and p38/JNK Signaling Pathway

Long Noncoding RNA GAS5 Promotes Osteogenic Differentiation of Human Periodontal Ligament Stem Cells by Regulating GDF5 and p38/JNK Signaling Pathway

Both extracellular matrix (ECM) and stem cells contribute to the formation of bones. Accumulating evidence proved that the growth differentiation factor 5 (GDF5) plays a vital role in ECM osteogenesis regulation; the use of human periodontal ligament stem cells (hPDLSCs) may contribute to alveolar b...

Full description

Bibliographic Details
Main Authors: Qiaolin Yang, Yineng Han, Peng Liu, Yiping Huang, Xiaobei Li, Lingfei Jia, Yunfei Zheng, Weiran Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Pharmacology
Subjects:
human periodontal ligament stem cells
osteogenic differentiation
long noncoding RNA
growth arrest specific transcript 5
growth differentiation factor 5
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00701/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00701/full

Similar Items