Synergy between Membrane Currents Prevents Severe Bradycardia in Mouse Sinoatrial Node Tissue
Bradycardia is initiated by the sinoatrial node (SAN), which is regulated by a coupled-clock system. Due to the clock coupling, reduction in the ‘funny’ current (I<sub>f</sub>), which affects SAN automaticity, can be compensated, thus preventing severe bradycardia. We hypothesize that th...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-03-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/24/6/5786 |