The human endogenous circadian system causes greatest platelet activation during the biological morning independent of behaviors.

The human endogenous circadian system causes greatest platelet activation during the biological morning independent of behaviors.

Platelets are involved in the thromboses that are central to myocardial infarctions and ischemic strokes. Such adverse cardiovascular events have day/night patterns with peaks in the morning (~9 AM), potentially related to endogenous circadian clock control of platelet activation. The objective was...

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Bibliographic Details
Main Authors: Frank A J L Scheer, Alan D Michelson, Andrew L Frelinger, Heather Evoniuk, Erin E Kelly, Mary McCarthy, Lauren A Doamekpor, Marc R Barnard, Steven A Shea
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3169622?pdf=render

Internet

http://europepmc.org/articles/PMC3169622?pdf=render

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