Nitrate-Functionalized poly(ε-Caprolactone) Small-Diameter Vascular Grafts Enhance Vascular Regeneration via Sustained Release of Nitric Oxide

Nitrate-Functionalized poly(ε-Caprolactone) Small-Diameter Vascular Grafts Enhance Vascular Regeneration via Sustained Release of Nitric Oxide

Artificial small-diameter vascular grafts (SDVG) fabricated from synthetic biodegradable polymers, such as poly(ε-caprolactone) (PCL), exhibit beneficial mechanical properties but are often faced with issues impacting their long-term graft success. Nitric oxide (NO) is an important physiological gas...

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Bibliographic Details
Main Authors: Sen Yang, Xueni Zheng, Meng Qian, He Wang, Fei Wang, Yongzhen Wei, Adam C. Midgley, Ju He, Hongyan Tian, Qiang Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
small-diameter vascular grafts
nitric oxide
vascular regeneration
vascular progenitor cells (VPCs)
vascular calcification
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.770121/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2021.770121/full

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