Molecular Evolution of the TET Gene Family in Mammals

Ten-eleven translocation (TET) proteins, a family of Fe2+- and 2-oxoglutarate-dependent dioxygenases, are involved in DNA demethylation. They also help regulate various cellular functions. Three TET paralogs have been identified (TET1, TET2, and TET3) in humans. This study focuses on the evolution o...

Full description

Bibliographic Details
Main Authors: Hiromichi Akahori, Stéphane Guindon, Sumio Yoshizaki, Yoshinori Muto
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/16/12/26110