High-throughput transcriptome profiling indicates ribosomal RNAs to be associated with resistance to immunotherapy in non-small cell lung cancer (NSCLC)

Background Despite the impressive outcomes with immune checkpoint inhibitor (ICI) in non-small cell lung cancer (NSCLC), only a minority of the patients show long-term benefits from ICI. In this study, we used retrospective cohorts of ICI treated patients with NSCLC to discover and validate spatiall...

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Bibliographic Details
Main Authors: David L Rimm, Kurt A Schalper, Myrto K Moutafi, Ioannis A Vathiotis, Niki Gavrielatou, Katherine M Bates, Thazin Nwe Aung, Rolando Garcia Milian, Vasiliki Xirou, Athanasios Angelakis, Leonidas Salichos
Format: Article
Language:English
Published: BMJ Publishing Group 2024-06-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/12/6/e009039.full