Deregulation of Negative Controls on TGF-β1 Signaling in Tumor Progression
The multi-functional cytokine transforming growth factor-β1 (TGF-β1) has growth inhibitory and anti-inflammatory roles during homeostasis and the early stages of cancer. Aberrant TGF-β activation in the late-stages of tumorigenesis, however, promotes development of aggress...
Main Authors: | Jiaqi Tang, Cody C. Gifford, Rohan Samarakoon, Paul J. Higgins |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-05-01
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Series: | Cancers |
Subjects: | |
Online Access: | http://www.mdpi.com/2072-6694/10/6/159 |
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