Estetrol Prevents Hot Flushes and Improves Quality of Life in Patients with Advanced Prostate Cancer Treated with Androgen Deprivation Therapy: The PCombi Study

Estetrol Prevents Hot Flushes and Improves Quality of Life in Patients with Advanced Prostate Cancer Treated with Androgen Deprivation Therapy: The PCombi Study

Background: Androgen deprivation therapy (ADT) for prostate cancer (PCa) is accompanied by side effects affecting health-related quality of life (HRQL). Objective: To assess the effects of the fetal estrogen estetrol (E4) on symptoms related to estrogen and androgen deficiency, and on HRQL measured...

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Bibliographic Details
Main Authors: Yvette Zimmerman, Mark Frydenberg, Hendrik van Poppel, R. Jeroen A. van Moorselaar, Erik P.M. Roos, Diederik M. Somford, Ton A. Roeleveld, Tjard D. de Haan, Harm H.E. van Melick, Yacov Reisman, Jan Krijgh, Frans M.J. Debruyne, Herjan J.T. Coelingh Bennink
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:European Urology Open Science
Subjects:
Advanced prostate cancer
Androgen deprivation therapy
Estetrol
Hot flushes
Health-related quality of life
Estrogen deficiency
Online Access:http://www.sciencedirect.com/science/article/pii/S2666168322019061

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http://www.sciencedirect.com/science/article/pii/S2666168322019061

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