Improving Fmoc Solid Phase Synthesis of Human Beta Defensin 3

Improving Fmoc Solid Phase Synthesis of Human Beta Defensin 3

Human β-defensin 3, HBD-3, is a 45-residue antimicrobial and immunomodulatory peptide that plays multiple roles in the host defense system. In addition to interacting with cell membranes, HBD-3 is also a ligand for melanocortin receptors, cytokine receptors and voltage-gated potassium channels. Stru...

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Bibliographic Details
Main Authors: Aleksandra Walewska, Paulina Kosikowska-Adamus, Marta Tomczykowska, Bartosz Jaroszewski, Adam Prahl, Grzegorz Bulaj
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
fmoc solid phase synthesis
cys residue protecting groups
pseudoproline dipeptides
disulfide bond
human beta defensin 3
selenocysteine
Online Access:https://www.mdpi.com/1422-0067/23/20/12562

Internet

https://www.mdpi.com/1422-0067/23/20/12562

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