Combination of indirect revascularization and endothelial progenitor cell transplantation improved cerebral perfusion and ameliorated tauopathy in a rat model of bilateral ICA ligation

Combination of indirect revascularization and endothelial progenitor cell transplantation improved cerebral perfusion and ameliorated tauopathy in a rat model of bilateral ICA ligation

Abstract Objective Endothelial progenitor cells (EPCs) contribute to the recovery of neurological function after ischemic stroke. Indirect revascularization has exhibited promising effects in the treatment of cerebral ischemia related to moyamoya disease and intracranial atherosclerotic disease. The...

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Bibliographic Details
Main Authors: Kuo-Chuan Wang, Ling-Yu Yang, Jing-Er Lee, Vicent Wu, Te-Fu Chen, Sung-Tsang Hsieh, Meng-Fai Kuo
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Stem Cell Research & Therapy
Subjects:
Endothelial progenitor cells
Microcirculation
Neuronal damage
Indirect revascularization
Angiogenesis
Cerebral ischemia
Online Access:https://doi.org/10.1186/s13287-022-03196-1

Internet

https://doi.org/10.1186/s13287-022-03196-1

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