Club Cell Loss as a Feature of Bronchiolization in ILD

Club Cell Loss as a Feature of Bronchiolization in ILD

Background: Distal airway metaplasia may precede honeycombing in progressive fibrosing interstitial lung disease (ILD). The SCGB1A1+ bronchiolar-specific club cell may play a role in this aberrant regenerative process.Objective: To assess the presence of club cells in the small airways of patients s...

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Bibliographic Details
Main Authors: Paul Reynaud, Engi Ahmed, Isabelle Serre, Lucie Knabe, Sébastien Bommart, Carey Suehs, Isabelle Vachier, Jean Philippe Berthet, Micaela Romagnoli, Charlotte Vernisse, Jean Pierre Mallet, Anne Sophie Gamez, Arnaud Bourdin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
club (clara) cell
idiopathic pulmonary fibrosis
metaplasia
SCGB1A1
bronchiolization
interstitial lung disease
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.630096/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.630096/full

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