Exploring the relationship between autophagy and Gefitinib resistance in NSCLC by silencing PDLIM5 using ultrasound-targeted microbubble destruction technology

Exploring the relationship between autophagy and Gefitinib resistance in NSCLC by silencing PDLIM5 using ultrasound-targeted microbubble destruction technology

Abstract Background Ultrasound-targeted microbubble destruction (UTMD) technology is a new drug and gene delivery strategy. This study investigates novel ultrasound (US) sensitive siRNA-loaded nanobubbles (siRNA-NBs) to explore the relationship between PDLIM5 mediated autophagy and drug resistance d...

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Bibliographic Details
Main Authors: Yao Zhang, Wenhao Lv, Hui Li, Tiantian Dong, Hao Wu, Chunhong Su, Hong Shu, Fang Nie
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Cancer Cell International
Subjects:
Ultrasound-targeted microbubble destruction
PDLIM5
Gene silencing
Nanobubbles
Non-small cell lung cancer
Online Access:https://doi.org/10.1186/s12935-022-02718-4

Internet

https://doi.org/10.1186/s12935-022-02718-4

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