The absence of AQP4/TRPV4 complex substantially reduces acute cytotoxic edema following ischemic injury

The absence of AQP4/TRPV4 complex substantially reduces acute cytotoxic edema following ischemic injury

IntroductionAstrocytic Aquaporin 4 (AQP4) and Transient receptor potential vanilloid 4 (TRPV4) channels form a functional complex that likely influences cell volume regulation, the development of brain edema, and the severity of the ischemic injury. However, it remains to be fully elucidated whether...

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Bibliographic Details
Main Authors: Petra Sucha, Zuzana Hermanova, Martina Chmelova, Denisa Kirdajova, Sara Camacho Garcia, Valeria Marchetti, Ivan Vorisek, Jana Tureckova, Eyar Shany, Daniel Jirak, Miroslava Anderova, Lydia Vargova
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Cellular Neuroscience
Subjects:
TRPV4
AQP4
ECS diffusion
MRI
cerebral ischemia
brain edema
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2022.1054919/full

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https://www.frontiersin.org/articles/10.3389/fncel.2022.1054919/full

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