The absence of AQP4/TRPV4 complex substantially reduces acute cytotoxic edema following ischemic injury
IntroductionAstrocytic Aquaporin 4 (AQP4) and Transient receptor potential vanilloid 4 (TRPV4) channels form a functional complex that likely influences cell volume regulation, the development of brain edema, and the severity of the ischemic injury. However, it remains to be fully elucidated whether...
Main Authors: | Petra Sucha, Zuzana Hermanova, Martina Chmelova, Denisa Kirdajova, Sara Camacho Garcia, Valeria Marchetti, Ivan Vorisek, Jana Tureckova, Eyar Shany, Daniel Jirak, Miroslava Anderova, Lydia Vargova |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-12-01
|
Series: | Frontiers in Cellular Neuroscience |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fncel.2022.1054919/full |
Similar Items
-
Astrocytic TRPV4 Channels and Their Role in Brain Ischemia
by: Jana Tureckova, et al.
Published: (2023-04-01) -
Reactive gliosis in traumatic brain injury: a comprehensive review
by: Zuzana Amlerova, et al.
Published: (2024-02-01) -
A view of the genetic and proteomic profile of extracellular matrix molecules in aging and stroke
by: Martina Chmelova, et al.
Published: (2023-11-01) -
Indirect Role of AQP4b and AQP4d Isoforms in Dynamics of Astrocyte Volume and Orthogonal Arrays of Particles
by: Marjeta Lisjak, et al.
Published: (2020-03-01) -
The pathogenesis of idiopathic normal pressure hydrocephalus based on the understanding of AQP1 and AQP4
by: Zitong Zhao, et al.
Published: (2022-09-01)