A mono-carbonyl analog of curcumin induces apoptosis in drug-resistant EGFR-mutant lung cancer through the generation of oxidative stress and mitochondrial dysfunction

A mono-carbonyl analog of curcumin induces apoptosis in drug-resistant EGFR-mutant lung cancer through the generation of oxidative stress and mitochondrial dysfunction

Xuanxuan Dai,1,* Junru Zhang,2,* Guilong Guo,1 Yuepiao Cai,3 Ri Cui,3 Changtian Yin,1 Weidong Liu,3 Rajamanickam Vinothkumar,3 Tingting Zhang,3 Guang Liang,3 Xiaohua Zhang1 1Department of Thyroid and Breast Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 32503...

Full description

Bibliographic Details
Main Authors: Dai X, Zhang J, Guo G, Cai Y, Cui R, Yin C, Liu W, Vinothkumar R, Zhang T, Liang G, Zhang X
Format: Article
Language:English
Published: Dove Medical Press 2018-08-01
Series:Cancer Management and Research
Subjects:
Epidermal growth factor receptor
reactive oxygen species
mono-carbonyl analog of curcumin
ER stress
mitochondrial dysfunction
apoptosis
NSCLC
Online Access:https://www.dovepress.com/a-mono-carbonyl-analog-of-curcumin-induces-apoptosis-in-drug-resistant-peer-reviewed-article-CMAR

Internet

https://www.dovepress.com/a-mono-carbonyl-analog-of-curcumin-induces-apoptosis-in-drug-resistant-peer-reviewed-article-CMAR

Similar Items