Structure of GrlR and the implication of its EDED motif in mediating the regulation of type III secretion system in EHEC.

Enterohemorrhagic Escherichia coli (EHEC) is a common cause of severe hemorrhagic colitis. EHEC's virulence is dependent upon a type III secretion system (TTSS) encoded by 41 genes. These genes are organized in several operons clustered in the locus of enterocyte effacement. Most of the locus o...

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Bibliographic Details
Main Authors: Chacko Jobichen, Mo Li, Gal Yerushalmi, Yih Wan Tan, Yu-Keung Mok, Ilan Rosenshine, Ka Yin Leung, J Sivaraman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-05-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC1868957?pdf=render