FLT3‐ITD mutations in acute myeloid leukaemia – molecular characteristics, distribution and numerical variation

FLT3‐ITD mutations in acute myeloid leukaemia – molecular characteristics, distribution and numerical variation

Recurrent somatic internal tandem duplications (ITD) in the FMS‐like tyrosine kinase 3 (FLT3) gene characterise approximately one third of patients with acute myeloid leukaemia (AML), and FLT3‐ITD mutation status guides risk‐adapted treatment strategies. The aim of this work was to characterise FLT3...

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Bibliographic Details
Main Authors: Caroline Engen, Monica Hellesøy, Tim Grob, Adil Al Hinai, Atle Brendehaug, Line Wergeland, Siv Lise Bedringaas, Randi Hovland, Peter J. M. Valk, Bjørn T. Gjertsen
Format: Article
Language:English
Published: Wiley 2021-09-01
Series:Molecular Oncology
Subjects:
acute myeloid leukaemia
FLT3‐ITD
length mutation
outcome
prognosis
Online Access:https://doi.org/10.1002/1878-0261.12961

Internet

https://doi.org/10.1002/1878-0261.12961

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